Translating every cell’s story.

Recent advances in circulating tumor cell (CTC) technologies provide a new alternative approach to examine proteomic and molecular characteristics of tumor cells from cancer patients. The current trend in anti-cancer drug development focuses on new compounds that modulate multiple signaling pathways, thus simultaneous examination of signaling pathways in CTCs at the single cell level can provide insight into drug activity in tumor cells.

ApoCell uses a multi-color, laser scanning cytometry (LSC)-based methodology to quantify and localize multiple biomarkers within the same CTC. Application of this technology in clinical studies to examine CTCs from patients could provide important information on pathway-specific drug activity and guide dosing selection.

Protein Expression

 

Protein Localization

 

Single Cell Multi-Marker Quantification