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Illuminating biomarker detection – Leading the way in personalized medicine.


1. What distinguishes ApoCell from other clinical research laboratories?
2. What experience or credentials are held by the scientific team of ApoCell?
3. How does one go about obtaining a quote for a project?
4. What stages of clinical trials does ApoCell support?
5. Does ApoCell have the capacity to receive specimens globally?
6. Does ApoCell maintain facilities outside of the US?
7. What role does ApoCell play in the discovery of novel biomarkers?
8. What is the extent of scientific consultation offered during development of a study?
9. Does ApoCell conduct studies outside of oncology?
10. Does ApoCell support murine or other non-human studies?
11. How are validation reports obtained by an interested client?

1. What distinguishes ApoCell from other clinical research laboratories?

There are three key aspects of the ApoCell business model that separate the company from more conventional specialized research organizations and clinical laboratories. First, ApoCell offers global clinical trial site management and advanced specimen handling and data analysis, in a single integrated service package. We are a one stop solution for supporting handling of patient specimens for clinical trial biomarker research. Second, ApoCell is a true research company. We are tightly integrated to academic science. Many of our scientists are veterans of the Texas Medical Center and/or have greater than 15 years industry experience. We routinely participate in academic collaborations, and actively publish our latest research and assays in peer reviewed journals. Our scientists can help you design custom assays for your pharmacodynamic research study based on our experience of 12 years of measuring the effects of biological and conventional therapies in different types of specimens. Lastly, we have an integrated technology platforms and state-of-the-art equipment that is interfaced to in-house and proprietary technology so that we can extend the boundaries of what is possible in the field of biomarker discovery and analysis.

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2. What experience or credentials are held by the scientific team of ApoCell?

Many of the scientists at ApoCell were trained at top medical research institutions such as the University of Texas M.D. Anderson Cancer Center or other prestigious institutions and many have held faculty positions at medical schools or management positions within industry. Most research scientists have a Ph.D. and/or an M.D. degree or greater than 15 years of industry experience. ApoCell also retains a panel of consulting scientists and clinicians from Baylor College of Medicine and MD Anderson for scientific guidance and for insight into the latest developments in the field.

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3. How does one go about obtaining a quote for a project?

You can request a quote for a project directly from our website by clicking on the request for proposal button on the left panel of each page. Our online quote systems provide you with the opportunity to describe the scope of work and services requested. One of our business development team members will help you generate a customized research program for your study or clinical trial. Alternatively, you can contact ApoCell directly at 713-440-6070 to speak with a member of the business development team.

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4. What stages of clinical trials does ApoCell support?

We support clinical trials at all stages, from pilot Phase 0 studies, through Phase I, II, and III trials. ApoCell specializes in collecting pharmacodynamic data for use in evaluating drug efficacy and validating diagnostic biomarkers. We also support studies for identifying prognostic markers and developing biomarker panels that can be used for patient stratification and personalized treatment protocols. While ApoCell primarily specializes in translation and clinical studies, we also support preliminary and basic research studies at earlier phases in drug development. Contact an ApoCell team member or request a project quote (see FAQ question 3) to learn more about how ApoCell biomarker strategies can be used to support your research study.

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5. Does ApoCell have the capacity to receive specimens globally?

ApoCell supports large and small clinical studies with trial sites from all over the world and can receive samples 365 days x 24hrs. We have established relationships with international and local shipping companies, which enable us to streamline sample shipping. Our proprietary, validated sample collection kits ensure the safe and stable transfer of clinical materials such as blood, over long transit distances. As part of our Clinical Trial Logistics Package, our sample collection specialists work to efficiently transfer samples from multiple sites to our facilities and serve as a central coordination hub for storing and standardizing patient and data information.

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6. Does ApoCell maintain facilities outside of the US?

ApoCell is currently based in the United States and we currently do not operate facilitates internationally, although we have arrangements with local vendors and shipping companies that allow us to efficiently coordinate the delivery of patient samples from all over the world.

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7. What role does ApoCell play in the discovery of novel biomarkers?

There are two aspects to biomarker discovery. Pilot studies to identify candidate markers that correlate to clinical outcome or drug efficacy; and validation studies to confirm the utility of the biomarker within a clinical population or trial. ApoCell actively participates in both of these aspects of biomarker discovery. We currently are executing discovery projects within the R&D program at ApoCell, in collaboration with academic investigators at medical centers, and with pharmaceutical companies worldwide.

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8. What is the extent of scientific consultation offered during development of a study?

To successfully monitor molecular events in clinical samples, it is critical to identify the subset of cells or biological material, in which the event is most likely to be observed; and to develop sensitive assays and the right biomarkers to generate informative decision-making information. ApoCell scientists can work with your group to develop protocols for the isolation and enrichment of established cell types or custom cell types of interest; and then customize assays for monitoring a panel of biomarkers relevant to the biological targets. Our scientists are available to help you at any of these development stages and we offer an R&D component to refine and validate an assay before deploying it in a larger scale clinical study.

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9. Does ApoCell conduct studies outside of oncology?

Historically, most of our projects have focused on cancer, although we have ongoing studies that involve the isolation of rare cells and the analysis of biomarkers in these cells for non-cancer diseases such as diabetes, inflammation, etc.

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10. Does ApoCell support murine or other non-human studies?

While ApoCell primarily specializes in translation and clinical studies with human samples, we also support preliminary and basic research studies at earlier phases in drug development. Our scientists have worked with companies and academic institutions that employ animal models and tissue culture-based assays. Our proof of concept studies usually involve tumor cell lines or xenograft tissues.

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11. How are validation reports obtained by an interested client?

We routinely validate assays that we develop at the company or for specific clinical studies. An existing validation report can be requested to potentially support assays for your study. If a validation report is not yet available or if we are developing a new customized assay, a validation report can be included in your research study.

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