Illuminating biomarker detection – Leading the way in personalized medicine.
“Erlotinib and bevacizumab in patients with recurrent or metastatic squamous-cell carcinoma of the head and neck: a phase I/II study”
Lancet. 2009 February 9, 2009 DOI:10.1016/S1470-2045(09)70002-6
“Automated quantitative analysis of activator protein-2alpha subcellular expression in melanoma tissue microarrays correlates with survival prediction.”
Cancer Res. 2005 Dec 1;65(23):11185-92.
“Pharmacodynamic analysis of target inhibition and endothelial cell death in tumors treated with the vascular endothelial growth factor receptor antagonists SU5416 or SU6668.”
Clin Cancer Res. 2005 Jan 15;11(2 Pt 1):678-89.
” Phase II study of the antiangiogenic agent SU5416 in patients with advanced soft tissue sarcomas.”
Clin Cancer Res. 2004 Sep 1;10(17):5732-40.
” Regional effects of an antivascular endothelial growth factor receptor monoclonal antibody on receptor phosphorylation and apoptosis in human 253J B-V bladder cancer xenografts.”
Cancer Res. 2004 Jul 1;64(13):4601-10.
“Quantitative analysis of biomarkers defines an optimal biological dose for recombinant human endostatin in primary human tumors.”
Clin Cancer Res. 2004 Jan 1;10(1 Pt 1):33-42.
“Surrogate markers in antiangiogenesis clinical trials.”
Br J Cancer. 2003 Jul 7;89(1):8-14. Review.
“Antiangiogenic Tumor Therapy.”
Antiangiogenic tumor therapy. Biotechniques. 2003 May;34(5):1048-50, 1052, 1054 passim. Review.
“Automated quantification of apoptosis after neoadjuvant chemotherapy for breast cancer: early assessment predicts clinical response.”
Clin Cancer Res. 2003 Mar;9(3):955-60.
” Development of Biologic Markers of Response and Assessment of Antiangiogenic Activity in a Clinical Trial of Human Recombinant Endostatin.”
J Clin Oncol. 2002 Sep 15;20(18):3804-14.
“Apoptosis and taxol therapy.”
Cancer Biol Ther. 2002 Mar-Apr;1(2):118-20.
“Endothelial Cell Apoptosis is Inhibited by a Soluble Factor Secreted by Human Colon Cancer Cells.”
Int. J. Cancer, 92:26-30, 2001.
“Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis.”
Cancer Res., 59: 5412-5416, 1999.